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- June 2003—Section 4, Drugs for Parasitic Infections
- July 2003—Section 3, Group B Streptococcal Infections
- August 2003—Section 3, Arboviruses
- Mid-August 2003—Section 2, School Health
- September 2003—Section 3, Influenza
- October 2003—Section 3, Respiratory Syncytial Virus
- November 2003—Foodborne Diseases: Appendix VI, Clinical Syndromes Associated With Foodborne Diseases and Appendix VII, Prevention of Disease From Potentially Contaminated Food Products
- December 2003—Section 3, Hepatitis A
- Mid-December 2003—Section 3, Influenza
- January 2004—Recommended Childhood and Adolescent Immunization Schedule — United States, January – June 2004
- Mid-January 2004—Section 3, Rotavirus Infections
- February 2004—Section 3, Prion Diseases: Transmissible Spongiform Encephalopathies
- Mid-February 2004—Section 2, Blood Safety: Reducing the Risk of Transfusion-Transmitted Infections
- March 2004—Section 3, Pertussis
- Mid-March 2004—Section 4, Tables of Antibacterial Drug Dosages: Table 4.1, Antibacterial Drugs for Newborn Infants and Table 4.2, Antibacterial Drugs for Pediatric Patients Beyond the Newborn Period
- April 2004—Section 3, Varicella-Zoster Infections
- Mid-April 2004—Section 2, Children in Out-of-Home Child Care
- May 2004—Section 3, Tuberculosis
- Mid-May 2004—Section 3, Diseases Caused by Nontuberculous Mycobacteria
- June 2004—Section 2, Bite Wounds
- Mid-June 2004—Waterborne Diseases, including Section 3, Cryptosporidiosis and Section 3, Amebic Meningoencephalitis and Keratitis (Naegleria fowleri, Acanthamoeba species, and Balamuthia mandrillaris)
- July 2004—Section 3, Giardia lamblia Infections (Giardiasis)
- Mid-July 2004—Appendix VIII, Diseases Transmitted by Animals
- August 2004—Section 3, Meningococcal Infections
- Mid-August 2004—Section 2, Sexually Transmitted Diseases in Adolescents and Children
- September 2004—Section 1, Vaccine Shortages
- Mid-September 2004—Appendix IX, Nationally Notifiable Infectious Diseases in the United States and Appendix IV, National Childhood Vaccine Injury Act. Reporting and Compensation Table.
- October 2004—Viral Gastroenteritis, including Adenovirus Infections, Astrovirus Infections, Caliciviruses, and Rotavirus Infections
- Mid-October 2004—Section 3, Respiratory Syncytial Virus
- November 2004—Section 2, Medical Evaluation of Internationally Adopted Children for Infectious Diseases
- Mid-November 2004—Section 3, Campylobacter Infections and Section 3, Salmonella Infections
- December 2004—Section 2, Infection Control for Hospitalized Children and Section 2, Infection Control in Physicians' Offices
- Mid-December 2004—Section 3, Staphylococcal Infections and Section 3, Group A Streptococcal Infections
- January 2005—Recommended Childhood and Adolescent Immunization Schedule — United States, 2005
- Mid-January 2005—Section 1, Minimum Ages and Minimum Intervals Between Vaccine Doses
- February 2005—Section 3, Influenza
- Mid-February 2005—Section 3, Meningococcal Infections
- March 2005—Section 1, Sources of Vaccine Information
- Mid-March 2005—Section 3, Rubella
- April 2005—Section 3, Pertussis
- Mid-April 2005—Section 3, Herpes Simplex
- May 2005—Section 2, Prevention of Tickborne Infections
- Mid-May 2005—Tickborne Diseases, including Section 3, Lyme Disease (Borrelia burgdorferi Infection) and Section 3, Rocky Mountain Spotted Fever
- June 2005—Section 3, Escherichia coli Diarrhea (Including Hemolytic-Uremic Syndrome)
- Mid-June 2005—Section 3, Hepatitis B
- July 2005—Section 1, International Travel
- Mid-July 2005—Section 1, Preterm and Low Birth Weight Infants
- August 2005—Section 2, Children in Out-of-Home Child Care
- Mid-August 2005—Section 2, School Health and Appendix V, State Immunization Requirements for School Attendance
- September 2005—Section 1, Vaccine Handling and Storage
- Mid-September 2005—Section 3, Varicella-Zoster Infections
- October 2005—Section 3, Influenza
- Mid-October 2005—Section 3, Respiratory Syncytial Virus and Section 3, Parainfluenza Viral Infections
- November 2005—Appendix VI, Clinical Syndromes Associated With Foodborne Diseases
- Mid-November 2005—Appendix VII, Prevention of Disease From Potentially Contaminated Food Products
- December 2005—Section 1, Parental Misconceptions About Immunizations
- Mid-December 2005—Section 3, Human Papillomavirus
- January 2006—Recommended Childhood and Adolescent Immunization Schedule: United States, 2006
- Mid-January 2006—Section 1, Minimum Ages and Minimum Intervals Between Vaccine Doses
- February 2006—Section 3, Influenza
- Mid-February 2006—Section 1, Informing Patients and Parents
- March 2006—Section 3, Group A Streptococcal Infections
- Mid-March 2006—Section 3, Varicella-Zoster Infections
- April 2006—Section 3, Parvovirus B19 (Erythema Infectiosum, Fifth Disease)
- Mid-April 2006—Section 3, Mumps
- May 2006—Section 3, Cryptosporidiosis
- Mid-May 2006—Section 2, Bite Wounds
- June 2006—Section 2, Medical Evaluation of Internationally Adopted Children for Infectious Diseases
- Mid-June 2006—Section 5, Antimicrobial Prophylaxis in Pediatric Surgical Patients
- July 2006—Section 1, Informing Patients and Parents
- August 2006—Summary of Major Changes in the 2006 Red Book
- September 2006—Section 3, West Nile Virus
- Mid-September 2006—Section 3, Escherichia coli Diarrhea (Including Hemolytic-Uremic Syndrome)
- October 2006—Section 3, Rotavirus Infections
- Mid-October 2006—Section 3, Influenza
- November 2006—Section 1, Vaccine Handling and Storage
- Mid-November 2006—Appendix VII, Prevention of Disease From Potentially Contaminated Food Products
- December 2006—Section 1, Immunocompromised Children
- Mid-December 2006—Section 2, Medical Evaluation of Internationally Adopted Children for Infectious Diseases
- January 2007—Recommended Childhood and Adolescent Immunization Schedules: United States, 2007, for Ages 0-6 and Ages 7-18
- February 2007—Appendix IX, Nationally Notifiable Infectious Diseases in the United States
- March 2007—Section 3, Rotavirus Infections
- April 2007—Section 3, Rocky Mountain Spotted Fever
- May 2007—Section 2, Prevention of Mosquitoborne Infections
- July 2007—Section 2, Prevention of Illnesses Associated with Recreational Water Use
- August 2007—Section 1, Adolescent and College Populations
- September 2007—Section 2, School Health
- October 2007—Section 3, Parainfluenza Viral Infections
- Mid-October 2007—Section 3, Respiratory Syncytial Virus
- November 2007—Section 3, Influenza
- Mid-November 2007—Appendix VII, Prevention of Disease From Potentially Contaminated Food Products
- December 2007—Section 1, Parental Misconceptions About Immunizations
- Mid-December 2007—Section 3, Haemophilus influenzae Infections
- January 2008—Recommended Childhood and Adolescent Immunization Schedules: United States, 2008, for Ages 0-6 and Ages 7-18
- February 2008—Appendix II, Standards for Child and Adolescent Immunization Practices
- Mid-February 2008—Section 1, Informing Patients and Parents
- March 2008—Section 3, Rotavirus Infections
- Mid-March 2008—Section 3, Pertussis (Whooping Cough)
- April 2008—Section 3, Parvovirus B19 (Erythema Infectiosum, Fifth Disease)
- May 2008—Section 3, Measles
- September 2008—Section 2, School Health
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