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Appendices

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Section 1. Active and Passive Immunization

Active Immunization

Immunizing Antigens

Physicians should be familiar with the major constituents of the products they use. The major constituents, including cell line derivation or animal derivatives, as relevant, are listed in the package inserts. If a vaccine is produced by different manufacturers, differences may exist in the active and/or inert ingredients and the relative amounts contained in the various products. The major constituents of vaccines include the following:

  • Active immunizing antigens. Some vaccines consist of a single antigen that is a highly defined constituent (eg, tetanus or diphtheria toxoid). In other vaccines, antigens that provoke protective immune responses vary substantially in chemical composition and number (eg, acellular pertussis components, Haemophilus influenzae type b, and pneumococcal . . . [Go to Full Text]